The HV2621/HV2721/HV2722 devices are 300V, low-charge injection, 16-channel, high-voltage analog switches. These devices are designed for use in applications requiring high-voltage switching controlled by low-voltage signals, such as medical ultrasound imaging, piezoelectric transducer drivers and panel testing etc. The performance of HV2621/HV2721 are almost identical to HV2601/2701 but have a larger input signal range. These devices are suitable for various combinations of high-voltage supplies, e.g., VPP/VNN: +60V/-240V, +150V/-150V, and +260V/-40V. If the VPP/VNN = ±150V, HV2621/HV2721/HV2722 can pass an analog signal up to ±135V. The HV2721 has integrated bleed resistors on both sides of the switches. The HV2722 has integrated bleed resistors on one side, SWxA only. The HV2621 has no bleed resistors.