The ADS112U04 is a precision, 16-bit, analog-to-digital converter (ADC) that offers many integrated features to reduce system cost and component count in applications measuring small sensor signals. The device features two differential or four single-ended inputs through a flexible input multiplexer (MUX), a low-noise, programmable gain amplifier (PGA), two programmable excitation current sources, a voltage reference, an oscillator, and a precision temperature sensor. The device can perform conversions at data rates up to 2000 samples-per-second (SPS) with single-cycle settling. At 20 SPS, the digital filter offers simultaneous 50-Hz and 60-Hz rejection for noisy industrial applications. The internal PGA offers gains up to 128. This PGA makes the ADS112U04 ideally suited for applications measuring small sensor signals, such as resistance temperature detectors (RTDs), thermocouples, thermistors, and resistive bridge sensors. The ADS112U04 features a 2-wire, UART-compatible interface. In applications that require galvanic isolation this universal asynchronous receiver/transmitter (UART) interface minimizes the number of digital isolation channels, thus saving cost, board space, and power. The ADS112U04 is offered in a leadless 16-pin WQFN or a 16-pin TSSOP package and is specified over a temperature range of –40°C to +125°C.