The TUSB216I is a third-generation USB 2.0 high-speed signal conditioner designed to compensate both AC loss (due to capacitive load) and DC loss (due to resistive loss) in the transmission channel. The TUSB216I leverages a patented design to speed-up transition edges of USB 2.0 high-speed signal with an edge booster and increases static levels with a DC boost function. In addition, the TUSB216I includes a pre-equalization function to improve the receiver sensitivity and compensate the inter-symbol interference (ISI) jitter in application with longer cable length. USB low-speed and full-speed signal characteristics are unaffected by the TUSB216I. The TUSB216I improves signal quality without altering packet timing or adding propagation delay or latency. The TUSB216I helps a system to pass the USB 2.0 high-speed near end eye compliance with a cable as long as 5 meters. The TUSB216I is compatible with the USB On-The-Go (OTG) and battery charging (BC 1.2) protocols. The Integrated BC 1.2 battery charging controller can be enabled through a control pin.