The ISO1640, ISO1641, ISO1642, ISO1643 and ISO1644 (ISO164x) device s are hot swappable, low-power, bidirectional isolator s that are compatible with I2C interfaces. The ISO164x supports UL 1577 isolation ratings of 5000 VRMS in the 16-DW package, and 3000 VRMS in the 8-D package. Each I2C isolation channel in this low emissions device has a logic input and open drain output separated by a double capacitive silicon dioxide (SiO2) insulation barrier. The ISO1642 and ISO1643 intregrates 2 unidirectional CMOS isolation channels, while the ISO1644 intregrates 3 unidirectional CMOS isolation channels which can be used for static GPIO isolation or to isolate a Serial Peripheral Interface (SPI) bus. This family includes basic and reinforced insulation devices certified by VDE, UL, CSA, TUV and CQC. The ISO1640/2/3/4 have two isolated bidirectional channels for clock and data lines and the ISO1641 has a bidirectional data and a unidirectional clock channel. The ISO164x family integrates logic required to support bidirectional channels, providing a much simpler design and smaller footprint when compared to optocoupler-based solutions.