The ZSSC4161D is a high-performance CMOS IC for precise amplification and correction of Wheatstone bridge sensor signals. With digital compensation for offset, drift, and nonlinearity, it delivers excellent accuracy and reliability. Various self-supervision mechanisms allow monitoring for correct functionality during operation. Integrated non-volatile memory and digital calibration reduce assembly costs and eliminate external trimming. Focused for automotive use, the ZSSC4161D offers robust protection, excellent EMC, and easy calibration via I²C or OWI interface, making it the most efficient, cost-effective solution for sensor signal processing. The ZSSC4161D includes two different product derivatives: The ZSSC4161D-01 is optimized for I²C output interface, offers measurement of one Wheatstone bridge, temperature compensation with external P/N junction or internal temperature source. Bridge input signal amplification goes up to 200, A/D conversion up to 18 bits, and sample rates up to 1.48kHz. The ZSSC4161D-03 is optimized for SENT output interface, offers measurement of one Wheatstone bridge, temperature compensation with external P/N junction or internal temperature source. Bridge input signal amplification goes up to 200, A/D conversion up to 18 bits, and sample rates up to 1.48kHz. Operation in functional safety systems up to ASIL B is supported.