The RC22112A regenerates and distributes ultra-low jitter clock outputs and features up to six independent frequency domains that can be locked to a free-run crystal or oscillator. The device supports multiple independent reference clocks for high-speed serial links. Input-to-input, input-to-output, and output-to-output phase skew can all be precisely managed. The device outputs ultra-low-jitter clocks that can directly synchronize SerDes running at up to 56Gbps. The device is ideal for use in 100G/200G/400G/800G telecom switch fabric cards and OTN applications.