The NAFE33352-UIOM universal analog input/output (AIO) analog front end (AFE) Arduino shield board is easy to test and designed for the NAFE33352, which is a highly configurable, industrial-grade universal AIO AFE. This Arduino shield board enables compact hardware design and enhanced software configurability with universal Open-Cortex Microcontroller Software Interface Standard (CMSIS) driver packs. The shield board supports quick evaluation and plug-and-play compatibility with NXP microcontroller (MCU)—boards MCX-N and low pin count (LPC)—having an Arduino connector. Users can quickly generate analog output (voltage/currents) and perform voltage, current and temperature measurements—resistance temperature detector (RTD) and thermocouple—to reduce the development time of the final application.