The INA321 family is a series of rail-to-rail output, micropower CMOS instrumentation amplifiers that offer wide-range, single-supply, as well as bipolar-supply operation. The INA321 family provides low-cost, low-noise amplification of differential signals with micropower current consumption of 40µA. When shutdown, the INA321 has a quiescent current of less than 1µA. Returning to normal operations within nanoseconds, the shutdown feature makes the INA321 optimal for low-power battery or multiplexing applications. Configured internally for 5V/V gain, the INA321 offers exceptional flexibility with user-programmable external gain resistors. The INA321 reduces common-mode error over frequency and with CMRR remaining high up to 3kHz, line noise and line harmonics are rejected. The low-power design does not compromise on bandwidth or slew rate, making the INA321 ideal for driving sample Analog-to-Digital (A/D) converters as well as general-purpose applications. With high precision, low cost, and small packaging, the INA321 outperforms discrete designs, while offering reliability and performance.