The PGA280 is a high-precision instrumentation amplifier with digitally-controllable gain and signal integrity test capability. This device offers low offset voltage, near-zero offset and gain drift, excellent linearity, and nearly no 1/f noise with superior common-mode and supply rejection to support high-resolution precision measurement. The 36-V supply capability and wide, high-impedance input range comply with requirements for universal signal measurement. Special circuitry prevents inrush currents from multiplexer (MUX) switching. In addition, the input switch matrix enables easy reconfiguration and system-level diagnostics—overload conditions are indicated. The configurable general-purpose input/output (GPIO) offers several control and communication features. The SPI can be expanded to communicate with more devices, supporting isolation with only four ISO couplers. The PGA280 is available in a TSSOP-24 package and is specified from –40°C to +105°C. For all available packages, see the package option addendum at the end of the data sheet.