The THS4521, THS4522, and THS4524 family of devices are very low-power, fully differential amplifiers with rail-to-rail output and an input common-mode range that includes the negative rail. These amplifiers are designed for low-power data acquisition systems and high-density applications where power dissipation is a critical parameter, and provide exceptional performance in audio applications. The family includes single FDA (THS4521), dual FDA (THS4522), and quad FDA (THS4524) versions. These fully differential amplifiers feature accurate output common-mode control that allows for dc-coupling when driving analog-to-digital converters (ADCs). This control, coupled with an input common-mode range below the negative rail as well as rail-to-rail output, allows for easy interfacing between single-ended, ground-referenced signal sources. Additionally, these devices are ideally suited for driving both successive-approximation register (SAR) and delta-sigma (ΔΣ) ADCs using only a single +2.5V to +5V and ground power supply. The THS4521, THS4522, and THS4524 family of fully differential amplifiers is characterized for operation over the full industrial temperature range from –40°C to +85°C.