The LPV521 is a single, nanopower, 552nW amplifier designed for ultra-long-life battery applications. The operating voltage range of 1.6V to 5.5V coupled with typically 351nA of supply current make this device an excellent choice for RFID readers and remote-sensor nanopower applications. The device has an input common-mode voltage 0.1V over the rails, specified TCVOS, and voltage-swing-to-the-rail output performance. The LPV521 has a carefully designed CMOS input stage that outperforms competitors with typically 40fA IBIAS currents. This low input current significantly reduces IBIAS and IOS errors introduced in megohm resistance, high-impedance photodiode and charge sense applications. The LPV521 is a member of the PowerWise family, and has an exceptional power-to-performance ratio. The wide input common-mode voltage range, specified 1mV VOS and 3.5µV/°C TCVOS enables accurate and stable measurement for both high-side and low-side current sensing. EMI protection is designed into the device to reduce sensitivity to unwanted RF signals from cell phones or other RFID readers. The LPV521 is offered in 5-pin SC70 and 8-pin PDIP packages.